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Metabolic

NT-proBNP

LOINC 33762-6 · pg/mL

What it is

NT-proBNP is a fragment released by the heart when its walls are stretched or under strain. It is a key marker of heart-pumping stress.

Why it matters

It helps detect and monitor heart failure and is used to assess shortness of breath.

What high values can mean

A higher value suggests the heart is under more strain, as in heart failure; levels also rise with age and reduced kidney function.

What low values can mean

A lower value makes significant heart strain less likely.

How to improve it

NT-proBNP follows heart health; managing blood pressure, heart conditions and fluid balance as advised is key.

Food & lifestyle

A heart-healthy pattern — less salt, regular activity, not smoking — supports the heart over time.

Preparing for the test

A blood test; fasting is not usually required — follow your lab's instructions.

When to talk to a doctor

Seek prompt care for severe breathlessness; discuss an elevated NT-proBNP with a doctor.

Related markers

Sources

  • MedlinePlus (NIH)
  • Testing.com (AACC)

Content reviewed on June 26, 2026

Medical disclaimer

This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.

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