Metabolic
Lipase
LOINC 3040-3 · U/L
What it is
Lipase is an enzyme made mainly by the pancreas that helps digest fats. It is a key test when pancreas problems are suspected.
Why it matters
Lipase is more specific to the pancreas than amylase, making it a preferred test for pancreatitis.
What high values can mean
A higher value is most often linked to pancreatitis or other pancreatic conditions.
What low values can mean
A lower value is less common and is interpreted in the clinical context.
How to improve it
Lipase reflects pancreatic function; limiting heavy alcohol use supports pancreatic health.
Food & lifestyle
Avoiding excess alcohol and very high-fat binges supports the pancreas, a common factor in pancreatitis.
Preparing for the test
A blood test; fasting is not usually required — follow your lab's instructions.
When to talk to a doctor
Seek urgent care for severe abdominal pain; discuss an elevated lipase with a doctor.
Related markers
Sources
- MedlinePlus (NIH)
- Testing.com (AACC)
Content reviewed on June 26, 2026
Medical disclaimer
This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.
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