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Metabolic

HOMA-IR

LOINC 98979-8 · ratio

What it is

HOMA-IR is a calculated index of insulin resistance, worked out from your fasting glucose and fasting insulin together.

Why it matters

It estimates how well your body responds to insulin, an early window into metabolic health before glucose rises.

What high values can mean

A higher value suggests more insulin resistance — your body needs more insulin to manage blood sugar.

What low values can mean

A lower value suggests good insulin sensitivity.

How to improve it

Weight management, regular activity, a lower-refined-carb diet and good sleep are the most effective ways to improve insulin sensitivity.

Food & lifestyle

Fibre-rich whole foods, vegetables and protein help; sugary drinks, refined carbs and excess calories worsen resistance.

Preparing for the testFasting required

Requires fasting glucose and insulin drawn together — do not eat for 8–12 hours beforehand.

When to talk to a doctor

Discuss a high HOMA-IR with a doctor as part of your overall metabolic risk.

Related markers

Sources

  • Testing.com (AACC)
  • NIH (NCBI)

Content reviewed on June 26, 2026

Medical disclaimer

This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.

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